Target intelligence / Profile preview

Wolf-Hirschhorn syndrome candidate 1-like 2, pseudogene (WHSC1L2P)

Target
WHSC1L2P
Molecular classification
Other (pseudogene)
01

Overview

WHSC1L2P (Wolf-Hirschhorn syndrome candidate 1-like 2, pseudogene) is a human pseudogene related by sequence homology to the functional histone methyltransferases WHSC1 (NSD2/MMSET) and possibly WHSC1L1 (NSD3), both of which are implicated in epigenetic regulation through histone methylation, cell differentiation, and oncogenesis[2][4]. However, WHSC1L2P itself lacks protein-coding capacity and functional characterization; there is no evidence it encodes an active histone methyltransferase or participates in signaling pathways or cellular processes. Accordingly, it is not considered a therapeutic target, receptor, enzyme, transporter, or biomarker, and there are neither known drugs nor clinical applications associated with it[2]. Its annotation and aliases reflect its sequence similarity and historical naming conventions, but scientific literature does not attribute any biological activities, disease roles, or therapeutic significance to this pseudogene.

Other names
NSD4PHsT36289WHSC1L1PWolf-Hirschhorn syndrome candidate 1-like 1 pseudogene

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