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Wound healing and tissue regeneration refer to the complex, multi-phase biological processes that restore tissue integrity and function after injury. These processes involve hemostasis (blood clot formation), inflammation (innate immune response), cell migration and proliferation (including fibroblasts, keratinocytes, and endothelial cells), formation of new extracellular matrix and blood vessels (granulation tissue, angiogenesis), epithelialization (restoration of epithelial barriers), and tissue remodeling. Proper regulation orchestrates scar formation versus true tissue regeneration, and dysregulation can result in chronic wounds or excessive fibrosis. While many drugs and biologics aim to modulate individual pathways (such as growth factors or immune signals), "wound healing and tissue regeneration" is technically a process, not a specific druggable target[1][2][4][5][6]. Thus, "Wound healing and tissue regeneration" is best understood as a biological process rather than a single molecular target. Drugs and therapies often focus on modulating factors (e.g., VEGF, TGF-beta, interleukins) within this process but do not directly bind or target "wound healing and tissue regeneration" itself.
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