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X-linked inhibitor of apoptosis pseudogene 3 (XIAPP3) is annotated as a pseudogene related to the X-linked inhibitor of apoptosis protein (XIAP). Pseudogenes are genomic sequences similar to known genes but lacking coding potential for functional proteins and typically do not produce a functional product. XIAP, the functional gene, is a well-characterized inhibitor of apoptosis protein that regulates cell death by blocking caspase activity and has clear roles in cancer, immune regulation, and apoptosis pathways[1][2][3][4]. No evidence supports a functional, disease, or therapeutic role for XIAPP3, nor is it referenced among established therapeutic targets or biomarkers. All relevant literature and curated resources reference the protein-coding XIAP, not XIAPP3, for pharmacological intervention and biological function.
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