X-ray repair cross complementing 6 pseudogene 3 (XRCC6P3)

XRCC6P3 is officially designated as a pseudogene, meaning it is a non-functional segment of DNA resembling the protein-coding gene XRCC6 (which encodes Ku70, a DNA repair protein involved in non-homologous end-joining). XRCC6P3 does not produce a functional protein product and is not characterized as a biological target, receptor, enzyme, or disease-associated molecule in pharmacology or biomedicine. There is no evidence supporting a role for XRCC6P3 in any known biological process, disease, or as a target for drugs, nor is it considered a biomarker or associated with known therapeutic, diagnostic, or safety relevance[1]. The related functional gene, XRCC6, encodes a key protein (Ku70) involved in DNA double-strand break repair. However, XRCC6P3 lacks the sequences necessary for protein expression and biological activity[1]. XRCC6P3 is cataloged in databases such as NCBI Gene and Ensembl as a pseudogene and contains no record of association with disease, drug, or therapeutic targeting[1]. Sometimes, naming confusion may occur due to its alias “thyroid autoantigen 70kDa pseudogene,” but there is no evidence this gene segment produces an immunogenic protein or participates in thyroid autoimmunity. XRCC6P3 should not be considered a molecular target, and any assertion to the contrary is not supported by current scientific evidence[1].

Other names

X-ray repair complementing defective repair in Chinese hamster cells 6 pseudogene 3thyroid autoantigen 70kDa pseudogeneXRCC6P3