X-ray repair cross complementing 6 pseudogene 5 (XRCC6P5)

XRCC6P5 is a pseudogene in the human genome related to the XRCC6 gene family, which is involved in DNA double-stranded break repair via the nonhomologous end-joining pathway[2][3]. Unlike XRCC6 ("Ku70"), which plays critical roles in DNA repair, XRCC6P5 does not encode a functional protein and has no established biological or disease relevance, nor any associated drugs, mechanism of action, or biomarker utility in therapeutic contexts. Its annotation as a target is misleading, as pseudogenes generally do not have direct roles in molecular pharmacology or cellular signaling and are not considered druggable therapeutic targets. The presence of "pseudogene" in its name, and the lack of evidence for involvement in biological functions or disease, confirms this misclassification. Key information: - XRCC6P5 is not a receptor, enzyme, transporter, or transcription factor. - It does not participate in DNA repair or cellular signaling as a functional molecule. - It should not be considered a valid therapeutic target, and querying it as such is incorrect. If you require information about the functional gene XRCC6 (Ku70), which is a DNA repair protein and a valid target, clarification can be provided[2][3].

Other names

DNA repair protein, X-ray repair complementing defective repair in Chinese hamster cells 6 pseudogene 5X-ray repair complementing defective repair pseudogeneXRCC6P5