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XRCC1 N-terminal domain containing 1, C-terminal like pseudogene (XNDC1CP)

Target
XNDC1CP
Molecular classification
Pseudogene, Long non-coding RNA (lncRNA; likely, as many pseudogenes are classified as such), Other (non-protein-coding)
01

Overview

XRCC1 N-terminal domain containing 1, C-terminal like pseudogene (XNDC1CP) is a human pseudogene located on chromosome 11 (11:3,610,324-3,614,752), annotated as a processed, non-coding pseudogene homologous to the functional XRCC1 gene. Pseudogenes such as XNDC1CP typically do not code for functional proteins. While some pseudogenes can produce non-coding RNA transcripts that participate in the regulation of gene expression—such as by acting as miRNA decoys, sources of siRNAs, or by competing for RNA-binding proteins—specific evidence for any functional role of XNDC1CP is currently lacking.

Other names
XNDC1CPXNDC1 pseudogeneXRCC1 N-terminal domain containing 1, C-terminal like pseudogene
02

Mechanism of action

None (as a non-coding pseudogene, not a target for small molecule drugs or biologics) General note: Some pseudogenes regulate expression of their parent gene via competitive endogenous RNA (ceRNA) mechanisms, but this is not specifically demonstrated for XNDC1CP

03

Biological functions

No direct protein-coding or enzymatic functionPotential regulatory RNA function via transcript-mediated regulation, such as acting as a miRNA decoy or altering gene expression of parental genes (mechanisms inferred from known roles of other pseudogenes)
04

Disease associations

Other (no direct evidence for disease association for this pseudogene itself; its parent gene XRCC1 is associated with cancer, DNA repair, and stroke recovery, but no direct data link XNDC1CP to any disease)Pseudogenes as a class may play regulatory roles in various diseases, but specific evidence for XNDC1CP is lacking
05

Safety considerations

None known
06

Interacting drugs

None (no known drugs target this pseudogene or its transcript)
07

Biomarkers

None known

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