Yellow fever virus antigen

Yellow fever virus antigens refer to the viral proteins and epitopes derived from the structural and sometimes nonstructural proteins of yellow fever virus (YFV), a mosquito-borne flavivirus. The principal antigenic components recognized by the immune system are the three structural proteins: **capsid (C)**, **precursor membrane (prM)**, and **envelope (E)**. The E protein forms the surface of the mature virion and elicits strong neutralizing antibody responses, making it the dominant target for protective immunity and vaccine design[2][3][4][6]. Both T cell and B cell responses can be directed toward these antigens, which underlie the effectiveness of the YFV-17D vaccine[1][5]. In immunological research and clinical practice, detection of antibodies or T cell responses to these antigens serves as a marker of infection or successful immunization. Cross-reactivity with other flavivirus antigens is a recognized challenge for diagnostics and vaccine development[4][6]. **Note on “is_incorrect”:** The entry "Yellow Fever Virus Antigens" is a **category of structurally and functionally diverse viral proteins**, not a single molecular entity or druggable target in the sense of a receptor, enzyme, or transporter. Its role is as a collection of antigens, not a unique molecular target; for structured datasets, the canonical names would be individual proteins (e.g., “Yellow fever virus envelope protein”).

Other names

Yellow fever antigenYFV antigenYellow fever virus structural antigenYFV envelope proteinYFV capsid proteinYFV prM protein

Elicitation of adaptive immune responses (T cells/antibodies) targeting viral antigens Induction of neutralizing antibodies blocking viral entry