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The yellow fever virus (YFV) envelope (E) protein is a structural glycoprotein located on the surface of the virion. It is essential for viral infectivity, mediating attachment to host cell receptors and facilitating entry into cells via membrane fusion. The E protein is also the primary target for neutralizing antibodies and plays a central role in protective immunity, making it a key focus for vaccine development and antiviral strategies.
Neutralization of viral entry by antibodies
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