Target intelligence / Profile preview

Yersinia pestis V antigen (None)

Target: None
Molecular classification: Protein, Virulence factor

Overview

The V antigen, also known as LcrV, is a multifunctional virulence factor produced by *Yersinia pestis*, the bacterium responsible for plague. It plays a central role in the pathogenesis of infection and is essential for both bacterial virulence and immune evasion. It regulates the type III secretion system (T3SS) and modulates host immune responses, making it a crucial target for vaccine development and diagnostic tools.

Other names: LcrV

Mechanism of action

Antibody-mediated neutralization; modulation of immune response

Biological functions

Virulence regulationType III secretion system controlImmune modulationAntigen presentation

Disease associations

Infection

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