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YAP1P1 (Yes-associated protein 1 pseudogene 1) is a pseudogene related to the gene encoding Yes-associated protein 1 (YAP1), a transcriptional regulator in the Hippo signaling pathway[3]. Unlike YAP1, YAP1P1 does not produce a functional protein and is classified as a non-coding or unprocessed pseudogene; therefore, it does not serve as a therapeutic target, biomarker, or have established biological functions or disease roles. Its name sometimes causes confusion with the functional YAP1 gene, which is involved in cancer, organ size regulation, and other critical pathways[3]. Key clarifications: - YAP1P1 is not a receptor, enzyme, or signaling molecule. - It should not be confused with YAP1, an active transcription co-activator and major effector of the Hippo pathway[1][2][3][5]. - Some gene and protein databases note the existence of YAP1P1 only as a related sequence with no protein product or functional role[3]. If you intended to get information on the active protein YAP1, please specify, as YAP1 itself is a well-supported therapeutic target in multiple disease areas[1][2][3][4][5].
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