Target intelligence / Profile preview

ZBTB2 pseudogene 1 (ZBTB2P1)

Target
ZBTB2P1
Molecular classification
Other (pseudogene)
01

Overview

ZBTB2 pseudogene 1 (ZBTB2P1) is classified as a pseudogene and does not appear to encode a functional protein. Its canonical gene, ZBTB2, is a zinc finger and BTB domain-containing transcription factor involved in chromatin remodeling, DNA methylation-sensitive gene regulation, and stem cell differentiation. ZBTB2 has reported roles in cancer biology, especially in relation to p53 function and hypoxia signaling; however, there is no evidence that the pseudogene itself is expressed, has biological activity, or acts as a drug target. As such, "ZBTB2P1" is not considered a therapeutic target, nor does it have recognized aliases, disease associations, or bioactivity—its inclusion as a drug target is incorrect. The designation "ZBTB2P1" correctly refers to a pseudogene, not a functional molecule or receptor, and therefore does not meet the criteria for a therapeutic target. If information about the functional ZBTB2 protein is needed, refer instead to "Zinc finger and BTB domain-containing protein 2 (ZBTB2)".

Other names
ZBTB2P1ZBTB2 pseudogene 1

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