ZBTB7C antisense RNA 1 (ZBTB7C-AS1)

ZBTB7C antisense RNA 1 (ZBTB7C-AS1) is a long non-coding RNA transcribed from the genomic region antisense to the ZBTB7C gene[7][8]. As an antisense lncRNA, its primary function is likely regulation of ZBTB7C gene expression via RNA-mediated mechanisms, such as modulating the transcription, stability, or epigenetic state of the sense ZBTB7C locus[2][4]. While the specific biological or disease relevance of ZBTB7C-AS1 remains uncharacterized, such molecules often serve as fine regulators of their partner protein-coding genes, influencing processes that may be relevant in development, cancer, or cellular homeostasis[2][4]. Currently, ZBTB7C-AS1 is not recognized as a therapeutic target, and no drugs or biomarker strategies are described for it.

As an antisense lncRNA, it may regulate ZBTB7C (zinc finger and BTB domain containing 7C) gene expression through RNA-RNA hybridization, modulation of mRNA stability, changes in transcription, or chromatin remodeling