ZFHX3 antisense RNA 1 (ZFHX3-AS1)

**ZFHX3 antisense RNA 1 (ZFHX3-AS1)** is a **long non-coding RNA (lncRNA)**, also known as **AC004943.2**. It is transcribed antisense to the ZFHX3 gene and is believed to function primarily as a *cis-acting regulatory RNA*, modulating the expression of the ZFHX3 gene, which encodes a large zinc finger homeodomain transcription factor with critical roles in neuronal development, tumor suppression, and cardiac function[1][3][4]. ZFHX3-AS1 itself does not encode a protein and is not recognized as a direct therapeutic target (such as a receptor, enzyme, or transporter)[1][3]. Its major biological significance lies in its potential regulatory effect on the ZFHX3 gene, indirectly affecting processes such as cellular differentiation and disease phenotypes where ZFHX3 is involved. No small-molecule drugs or biologics are currently known to target ZFHX3-AS1 directly; nor is it used as a clinical biomarker or associated with safety concerns[1][3][4].

Other names

AC004943.2ZFHX3-AS1