Zinc finger and BTB domain-containing protein 26 (ZBTB26)

Zinc finger and BTB domain-containing protein 26 (ZBTB26) is a nuclear transcription factor that contains zinc finger motifs and a BTB domain, which enable sequence-specific double-stranded DNA binding and protein-protein interactions. The protein is predicted to be involved in the negative regulation of gene transcription mediated by RNA polymerase II, cytokine production, and regulation of immune system processes. It is primarily localized in the nucleus and nucleoplasm. ZBTB26 is a protein coding gene, with roles implicated in transcriptional regulation. A disease association is reported for congenital hypothyroidism, although its broader implications in disease are not well characterized. No drugs are currently known to interact with ZBTB26, and there are no established biomarkers or specific safety concerns related to this target. If further information on structure, interactions, or pathway context is needed, this protein's metabolic and physical interaction networks can be explored in resources like the Human Protein Atlas and UniProt.

Other names

Zinc finger and BTB domain-containing protein 26ZBTB26KIAA1572ZNF481Zinc finger protein 481Zinc finger protein BiorefZBTB26 (all caps)Zinc finger protein 483Znf481 (mouse)Zbtb26 (mouse)

Not applicable (no drugs targeting ZBTB26 are known)