Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Zinc finger and BTB domain-containing protein 8B (ZBTB8B)
- Target
- ZBTB8B
- Molecular classification
- Transcription factor, Zinc finger protein, BTB (POZ) domain-containing protein
01
Overview
Zinc finger and BTB domain-containing protein 8B (ZBTB8B) is a nuclear, DNA-binding transcription factor characterized by the presence of both zinc finger and BTB/POZ domains, which enable it to regulate gene expression, likely through interaction with DNA and other proteins[5][6]. It is highly enriched and functions in early lens development in the mouse, indicating a regulatory role in lens morphogenesis[1]. As a member of the ZBTB family, it may play roles in differentiation and tissue-specific regulation of gene expression, though its precise physiological and pathological roles in humans remain incompletely characterized[1][5][7]. There is no current evidence that it acts as a direct therapeutic target, nor are there any known drugs or specific biomarkers related to ZBTB8B[5]. Its expression has shown associations with some disease phenotypes and cancer, but mechanistic details and clinical applications remain to be elucidated[4][5].
- Other names
- Zinc finger and BTB domain-containing protein 8BZBTB8BRP1-27O5.1DKFZp547H154ZNF916Bputative zinc finger and BTB domain-containing protein 8B
02
Biological functions
Regulation of transcription by RNA polymerase IILikely involved in cell differentiationDNA-binding transcription factor activity
03
Disease associations
Cancer (limited evidence via expression analyses)Myopathy, distal, with anterior tibial onsetDystonia 11, myoclonic
Beyond the preview
Go deeper on Zinc finger and BTB domain-containing protein 8B (ZBTB8B).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Zinc finger and BTB domain-containing protein 8B (ZBTB8B).