Target intelligence / Profile preview

Zinc finger and SCAN domain-containing protein 29 (ZSCAN29)

Target
ZSCAN29
Molecular classification
Transcription factor, C2H2-type zinc finger protein, SCAN domain-containing protein
01

Overview

Zinc finger and SCAN domain-containing protein 29 (ZSCAN29) is a transcription factor characterized by the presence of both a C2H2-type zinc finger motif and a SCAN domain. The zinc finger domain enables specific DNA binding, allowing ZSCAN29 and other family members to regulate gene expression by targeting cis-acting DNA elements[1][2]. The SCAN domain mediates protein-protein interactions, including homo- and heterodimerization with other transcription factors, affecting transcriptional activity[1][3]. ZSCAN29 and the wider ZSCAN family are increasingly studied for their roles in gene expression modulation and potential involvement in cancer progression, differentiation, proliferation, and apoptosis; however, direct functional studies or disease links for ZSCAN29 itself remain limited in the published literature[1][2][3].

Other names
ZSCAN29ZNF690FLJ35867Zfp690Zinc finger protein 690KOX31-like zinc finger protein
02

Biological functions

Transcriptional regulation (via DNA binding)Protein-protein interactions (through the SCAN domain)Chromatin and gene expression modulation
03

Disease associations

Other (as a member of the ZSCAN family, ZSCAN29 may have relevance to cancer progression through transcriptional regulation[1], but specific disease roles for ZSCAN29 itself are not established in the literature)

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