Target intelligence / Profile preview

Zinc finger and SCAN domain-containing protein 5C (ZSCAN5C)

Target
ZSCAN5C
Molecular classification
Transcription factor, Zinc finger protein, SCAN domain protein
01

Overview

Zinc finger and SCAN domain-containing protein 5C (ZSCAN5C) is a member of the zinc finger transcription factor family containing a SCAN dimerization domain. It is encoded by a gene that appears to be protein-coding but has also been annotated as a pseudogene, reflecting potential ambiguity in its expression and functional relevance. ZSCAN5C is predicted to enable transcriptional regulation via DNA binding, primarily acting as a transcription factor with specificity for RNA polymerase II and possibly modulating chromatin architecture. There are no established therapeutic agents, recognized clinical biomarkers, or direct evidence of significant disease associations, beyond a reported genetic link to Anauxetic Dysplasia 1. Related family members (ZSCAN5A, ZSCAN5B, ZSCAN5D) are expressed in proliferating cells and may influence cell cycle progression, but the specific functional profile and biological activities of ZSCAN5C remain incompletely defined[1][2][3][4][5].

Other names
ZSCAN5CZinc finger and SCAN domain-containing protein 5CZSCAN5CPZNF495CZinc finger and SCAN domain-containing protein 5C pseudogeneZinc finger and SCAN domain-containing protein 5-like protein 2Putative zinc finger and SCAN domain-containing protein 5C
02

Biological functions

Transcriptional regulationDNA bindingRegulation of transcription by RNA polymerase II
03

Disease associations

Anauxetic Dysplasia 1 (reported genetic association)Other (no direct or strong disease roles identified for ZSCAN5C specifically; related ZSCAN5 family proteins may be involved in cell cycle regulation and mitosis)

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