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Zinc finger and SCAN domain-containing protein 5C (ZSCAN5C) is a member of the zinc finger transcription factor family containing a SCAN dimerization domain. It is encoded by a gene that appears to be protein-coding but has also been annotated as a pseudogene, reflecting potential ambiguity in its expression and functional relevance. ZSCAN5C is predicted to enable transcriptional regulation via DNA binding, primarily acting as a transcription factor with specificity for RNA polymerase II and possibly modulating chromatin architecture. There are no established therapeutic agents, recognized clinical biomarkers, or direct evidence of significant disease associations, beyond a reported genetic link to Anauxetic Dysplasia 1. Related family members (ZSCAN5A, ZSCAN5B, ZSCAN5D) are expressed in proliferating cells and may influence cell cycle progression, but the specific functional profile and biological activities of ZSCAN5C remain incompletely defined[1][2][3][4][5].
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