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Target intelligence / Profile preview
Zinc finger and SCAN domain-containing protein 9 (ZSCAN9)
- Target
- ZSCAN9
- Molecular classification
- Transcription factor, Zinc finger protein
01
Overview
Zinc finger and SCAN domain-containing protein 9 (ZSCAN9) is a sequence-specific DNA-binding transcription factor predicted to regulate transcription by RNA polymerase II[1][2]. It contains a C2H2-type zinc finger domain, which enables DNA binding, and a SCAN domain that mediates homodimer and selective heterodimer formation with other SCAN domain-containing transcription factors, influencing the transcriptional activity and regulatory networks of gene expression[3]. While the ZSCAN family is recognized for roles in cell differentiation, proliferation, and cancer biology, specific biological functions or disease associations for ZSCAN9 remain largely uncharacterized[2][3]. ZSCAN9 is primarily localized to the nucleus[2].
- Other names
- ZSCAN9ZNF193PRD51PIG12Cell proliferation-inducing gene 12 proteinZinc finger protein 193
02
Mechanism of action
Not applicable; no known drugs target ZSCAN9 directly
03
Biological functions
Regulation of transcription by RNA polymerase IISequence-specific double-stranded DNA binding
04
Disease associations
There is no specific disease association directly supported for ZSCAN9, but the broader ZSCAN family is implicated in cancer, especially regarding transcriptional regulation impacting cell proliferation and development[3].
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