Zinc finger CCCH-type containing 8 (ZC3H8)

ZC3H8 is a protein-coding gene that enables RNA binding activity. It is involved in various biological processes, including transcription regulation and the regulation of thymocyte apoptosis. ZC3H8 functions as a transcriptional repressor and plays a role in maintaining organ homeostasis by inhibiting NF-κB-mediated inflammation. It is part of the little elongation complex (LEC), which is crucial for regulating snRNA transcription by RNA polymerases II and III. ZC3H8 is associated with diseases such as Villous Adenocarcinoma and Retinitis Pigmentosa 38.

Other names

ZC3HDC8FLIZ1

Acts as a transcriptional repressor; maintains organ homeostasis by inhibiting NF-κB-mediated inflammatory response.