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Zinc finger protein 17 (ZNF17)
- Target
- ZNF17
- Molecular classification
- Transcription factor, C2H2-type zinc finger protein, DNA-binding protein
01
Overview
Zinc finger protein 17 (ZNF17) is a predicted DNA-binding transcription factor belonging to the C2H2-type zinc finger protein family. Like other members of this large and diverse group, ZNF17 is predicted to regulate gene expression by binding specific DNA sequences and modulating RNA polymerase II activity. It contains finger-like structural motifs stabilized by zinc ions and is active in the nucleus. While ZNF17 itself does not have well-characterized roles in human disease, C2H2-type zinc finger proteins as a class play essential functions in transcriptional regulation, cell differentiation, and development and are implicated in numerous cellular processes and diseases
- Other names
- KOX10HPF3KIAA1947FLJ40864FLJ46058FLJ46615Zinc finger protein HPF3Zinc finger protein KOX10
02
Biological functions
Regulation of transcription by RNA polymerase IISequence-specific DNA bindingPossibly regulation of gene expression
03
Disease associations
Other (no direct association with specific diseases is established for ZNF17; however, zinc finger proteins as a family are broadly implicated in cancer, neurodegeneration, and other conditions)
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