Target intelligence / Profile preview

Zinc finger protein 174 (ZNF174)

Target
ZNF174
Molecular classification
Transcription factor
01

Overview

Zinc finger protein 174 (ZNF174) is a member of the ZSCAN (zinc finger and SCAN domain-containing) family of transcription factors, characterized by possession of three C2H2-type zinc fingers at the carboxy-terminus and a SCAN domain at the amino-terminus, enabling self-dimerization[1][2]. It is believed to function primarily as a transcriptional repressor, binding to DNA to regulate gene expression, although the specific biological pathways and target genes remain under-characterized[2][3]. ZNF174 shows broad expression and several transcript isoforms exist due to alternative splicing[3]. Current literature does not identify it as a major therapeutic target nor link it strongly to specific disease mechanisms or drug interactions.

Other names
ZSCAN8AW-1Zinc finger and SCAN domain-containing protein 8ZNF174zinc finger protein 174zinc finger and SCAN domain-containing protein 8
02

Biological functions

Transcriptional repressionDNA bindingRegulation of gene expression
03

Disease associations

Other (associated with Long QT syndrome, but not strongly established as a disease target)

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