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Zinc finger protein 181 (ZNF181) is a member of the large zinc finger protein family, characterized by the presence of C2H2-type zinc finger domains that facilitate binding to DNA and function as a transcription factor[1][2][3][4]. ZNF181 is involved in the regulation of gene expression by RNA polymerase II and is predicted to participate in diverse cellular processes typical of zinc finger transcription factors, such as modulation of transcriptional activity and possibly RNA binding[4]. As with many zinc finger proteins, specific biological functions, disease associations, and drug interactions for ZNF181 remain incompletely characterized; its primary established role is as a DNA-binding transcription factor with diverse regulatory capabilities[1][3][4].
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