Zinc finger protein 222 (ZNF222)

Zinc finger protein 222 (ZNF222) is a member of the C2H2-type zinc finger protein family, characterized by the presence of multiple zinc finger motifs that coordinate zinc ions to create a stable structure capable of binding DNA. Zinc finger protein 222 acts as a transcription factor, regulating gene expression by interacting with specific DNA sequences, functioning primarily through RNA polymerase II. The broad class of zinc finger proteins, to which ZNF222 belongs, is involved in various biological processes, including DNA binding, metal ion binding, nucleic acid binding, and gene regulation. As with other zinc finger proteins, the functional diversity allows participation in processes such as cell differentiation, apoptosis, and development, although no specific therapeutic or drug interactions or validated disease associations have been directly established for ZNF222 in the available literature.

Other names

ZNF222zinc finger protein 222