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Zinc finger protein 3 homolog (ZFP3)
- Target
- ZFP3
- Molecular classification
- Transcription factor, Zinc finger protein (C2H2-type)
01
Overview
Zinc finger protein 3 homolog (ZFP3) is a member of the C2H2-type zinc finger transcription factors, predicted to function as a DNA-binding transcription factor regulating transcription via RNA polymerase II[3]. ZFP3 contains characteristic zinc finger motifs involved in DNA recognition and is part of the largest family of transcription regulators in the human genome[2][3]. In model organisms, ZFP3 homologs are associated with transcriptional responses to environmental stress or development, but for the human ortholog, strong evidence for a direct functional or disease role is limited. There are no known drug interactions or uses as a clinical biomarker, and ZFP3 itself is not currently recognized as a therapeutic target or disease-associated gene in humans[3].
- Other names
- Zinc finger protein 3 homologZFP3ZNF752Zfp-3FLJ30726Zinc finger protein 752zinc finger protein 3 homologzfp-3zinc finger protein 752zinc finger protein homologous to Zfp-3 in mousezinc finger protein-3
02
Biological functions
Transcription regulationDNA bindingRegulation of gene expressionPossibly involved in developmental processes and stress responses (as suggested from plant orthologs)
03
Disease associations
Other (Zinc finger proteins as a class are implicated in cancer and other diseases, but there is no direct evidence that ZFP3 itself plays a specific disease role in humans)
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