Target intelligence / Profile preview

Zinc finger protein 30 (ZNF30)

Target
ZNF30
Molecular classification
Transcription factor, Zinc finger protein, DNA-binding protein
01

Overview

Zinc finger protein 30 is a protein encoding gene in humans. It is a member of the zinc finger protein family and acts as a DNA-binding transcription factor, probably involved in the regulation of gene expression mediated by RNA polymerase II. ZNF30 proteins contain zinc finger domains which facilitate interaction with DNA, allowing transcriptional regulation. ZNF30 is predicted to be nuclear and has paralogs such as ZNF540. Genetic variations at the ZNF30 locus are associated with certain chromosome deletion syndromes and neurogenic disorders. Zinc finger proteins, including ZNF30, are important in gene regulatory networks but ZNF30 itself is not an established therapeutic target, nor is it known to interact with any drugs. If you need structured data for druggable zinc finger proteins (e.g., zinc finger nucleases), these are distinct from ZNF30, which is a conventional endogenous transcription factor and not targeted by current therapeutics.

Other names
ZNF30Zinc finger protein 30
02

Biological functions

Transcriptional regulationNucleic acid bindingDNA-binding transcription factor activity (RNA polymerase II-specific)
03

Disease associations

Chromosome 19q13.11 deletion syndromeArthrogryposis multiplex congenita 2, neurogenic typeOther; roles implied by locus effects, but no major direct disease mechanisms described

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