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Zinc finger protein 317 (ZNF317)
- Target
- ZNF317
- Molecular classification
- Transcription factor, Zinc finger protein, KRAB domain-containing protein
01
Overview
Zinc finger protein 317 (ZNF317) is a human protein encoded by the ZNF317 gene that belongs to the large family of zinc finger transcription factors, specifically those with a KRAB domain. It is predicted to act as a transcription factor regulating the expression of target genes by binding to cis-regulatory DNA regions, with possible roles in erythroid cell maturation and lymphoid cell proliferation. While disorders such as female stress incontinence and frontometaphyseal dysplasia have been associated with this gene, there is no current evidence supporting its use as a therapeutic target or that drugs directly interact with it[2][5][7].
- Other names
- ZNF317KIAA1588KRAB-containing zinc finger protein 317
02
Biological functions
Regulation of transcription by RNA polymerase IIErythroid maturationLymphoid proliferationDNA binding
03
Disease associations
Female stress incontinenceFrontometaphyseal dysplasia
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