Target intelligence / Profile preview

Zinc finger protein 324B (ZNF324B)

Target
ZNF324B
Molecular classification
Transcription factor, Zinc finger protein (C2H2-type; KRAB domain-containing)
01

Overview

Zinc finger protein 324B (ZNF324B) is a member of the large C2H2-type zinc finger protein family, which functions as a DNA-binding transcription factor and is involved in the regulation of gene expression. ZNF324B contains multiple zinc finger domains, including a KRAB (Krüppel-associated box) domain, which are characteristic of proteins capable of mediating sequence-specific interactions with DNA and modulating transcriptional activity. While the precise physiological and pathological roles of ZNF324B are not fully elucidated, proteins in this family are known to regulate processes such as cell proliferation, differentiation, apoptosis, and responses to external signals. ZNF324B expression has been observed in various cancer types, suggesting it could play a role in oncogenic pathways or cancer biology, though there is no evidence of it being a direct therapeutic target or a current biomarker.

Other names
ZNF324BFLJ45850Zinc finger protein 324B
02

Biological functions

Transcriptional regulation (acts as transcriptional activator or repressor depending on cellular context)Regulation of gene expressionMay participate in cell proliferation and differentiation
03

Disease associations

Cancer (expression observed in various cancer tissues; broader disease roles are not well established)Other (generic reference to possible involvement in developmental processes based on zinc finger family functions)

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