Target intelligence / Profile preview

Zinc finger protein 343 (ZNF343)

Target
ZNF343
Molecular classification
Transcription factor, C2H2-type zinc finger protein, Krueppel C2H2-type zinc finger protein family
01

Overview

Zinc finger protein 343 (ZNF343) is a human protein encoded by the ZNF343 gene and belongs to the large family of C2H2-type zinc finger transcription factors[3][4][5][11]. It contains characteristic C2H2 zinc finger motifs and is predicted to function in sequence-specific double-stranded DNA binding with a role in regulating transcription by RNA polymerase II within the nucleus[2][3][7][9]. Like other zinc finger proteins, it may be involved in a range of cellular processes by influencing gene expression, but there is no current evidence supporting its use as a direct therapeutic target or established disease biomarker[1][4][9].

Other names
MGC10715dJ734P14.5DJ734P14.5ZN343_HUMAN
02

Biological functions

Regulation of transcription by RNA polymerase IISequence-specific double-stranded DNA bindingNucleic acid bindingTranscriptional regulation
03

Disease associations

Potential association with Endometrial mixed adenocarcinomaOther (no established major disease link)

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