Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Zinc finger protein 354A (ZNF354A)
- Target
- ZNF354A
- Molecular classification
- Transcription factor, Zinc finger protein, DNA-binding protein
01
Overview
Zinc finger protein 354A (ZNF354A) is a protein-coding transcription factor expressed in humans, characterized by one or more zinc finger motifs that coordinate zinc ions and stabilize its DNA-binding structure[1][3][5][6]. As a member of the Cys2His2 (C2H2)-type zinc finger protein family, it regulates gene expression by binding DNA in a sequence-specific manner and is involved in numerous cellular processes, mainly transcriptional regulation[1][2][3][5][6]. ZNF354A is predominantly localized in the cytosol, nucleolus, and nucleoplasm and is associated with cancer as a biomarker. The gene encoding ZNF354A is also expressed in various tissues and cell lines, with high-throughput data linking it to diverse molecular networks[4][5].
- Other names
- KID1EZNFHEL104HKL1KID-1TCF17ZFP354AZpf354aTranscription factor 17epididymis luminal protein 104
02
Biological functions
Transcription regulationGene expressionDNA binding
03
Disease associations
Cancer (notably as a biomarker for in situ carcinoma and seminoma)Paraphimosis (listed in disease associations, but unclear mechanistic role)
04
Biomarkers
In situ carcinoma (biomarker of disease presence)Seminoma
Beyond the preview
Go deeper on Zinc finger protein 354A (ZNF354A).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Zinc finger protein 354A (ZNF354A).