Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Zinc finger protein 385D (ZNF385D)
- Target
- ZNF385D
- Molecular classification
- Transcription factor, Zinc finger protein, C2H2-type zinc finger superfamily
01
Overview
Zinc finger protein 385D (ZNF385D) is a sequence-specific DNA-binding transcription factor belonging to the C2H2-type zinc finger superfamily, localized in the nucleus and predicted to be crucial for neural development—particularly in processes underlying higher order language and communication[1][3]. Genome-wide association studies have found significant links between variations in ZNF385D and co-occurring reading disability and language impairment, implicating this factor in the regulation of genes essential for the formation of neural circuits and brain connectivity supporting language acquisition. ZNF385D is not recognized as a canonical pharmacological target such as a receptor, enzyme, or transporter, nor are there approved drugs that act upon it or established safety concerns documented in the current literature[1][3].
- Other names
- Zinc finger protein 659ZNF659FLJ22419
02
Biological functions
Sequence-specific double-stranded DNA bindingRegulation of gene expressionNeural developmentPotential role in higher order language and communication skills
03
Disease associations
Neurodevelopmental disorders (notably, associated with reading disability and language impairment)Potential relevance in structural brain connectivity and neural circuit formationNo current evidence for a primary role in cancer, inflammation, infection, or major systemic diseases in humans
04
Biomarkers
Genetic association with reading disability and language impairmentNo established use as a clinical biomarker for therapy monitoring
Beyond the preview
Go deeper on Zinc finger protein 385D (ZNF385D).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Zinc finger protein 385D (ZNF385D).