Zinc finger protein 397 pseudogene

Zinc finger protein 397 pseudogene" is a non-functional genomic sequence similar to the protein-coding gene zinc finger protein 397 (ZNF397). Pseudogenes are generally considered to be non-functional copies of genes that lack protein-coding ability due to mutations, premature stop codons, frameshifts, or improper splice sites[2]. As a result, this gene is not considered a therapeutic target, does not produce a functional protein, and is not involved in biological or disease processes relevant to therapies[2]. There are no known drugs or mechanisms of action associated with this pseudogene, nor is it used as a biomarker or linked to any safety concerns. The canonical, functional version is "zinc finger protein 397" (ZNF397), which is a DNA-binding transcription factor[1]. The requested Ensembl entry (ENSG00000278683) designates a pseudogene, meaning it is not the protein-coding, functional ZNF397. As a pseudogene, it is considered incorrect to treat it as a receptor, enzyme, drug target, or disease gene. Zinc finger proteins (ZFPs) are a large family of DNA-binding proteins with roles in gene regulation, but pseudogenes of these proteins are not functionally active[2][3]. ENSG00000278683 ("zinc finger protein 397 pseudogene") is a pseudogene, not a functional protein or drug target, and should not be used as such in therapeutic target lists. If you are interested in the functional protein, you should refer to "zinc finger protein 397" (ZNF397, ENSG00000186812)[1][2].

Other names

ZNF397P