Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Zinc finger protein 428 (ZNF428)
- Target
- ZNF428
- Molecular classification
- Transcription factor, Zinc finger protein (C2H2-type), DNA-binding protein
01
Overview
Zinc finger protein 428 (ZNF428) is a ubiquitously expressed nuclear and cytoplasmic protein in humans, containing classical zinc finger domains that enable it to bind DNA and potentially regulate transcription. The gene is located on chromosome 19 (19:43,607,223-43,619,639; reverse strand) and has several transcripts. Zinc finger proteins form one of the largest protein families, characterized by DNA, RNA or protein-binding functions, and are widely involved in transcriptional regulation, differentiation, development, and other cellular processes. While several related zinc finger proteins are implicated in disease (cancer, neurodegeneration), there is currently no published evidence specifically linking ZNF428 itself to any disease state or known drug interactions.
- Other names
- C19orf37MGC51082Zfp428Enzyme-like protein PIT13 (rare/obsolete)ENSG00000131116 (Ensembl ID)
02
Biological functions
Predicted: Metal (zinc) ion bindingRegulation of gene expression (likely transcriptional regulation, as typical for zinc finger proteins)
03
Disease associations
No specific diseases currently linked to ZNF428; other zinc finger proteins are involved in cancer, neurodegeneration, diabetes, and skin disease, but direct roles for ZNF428 in disease are not established
Beyond the preview
Go deeper on Zinc finger protein 428 (ZNF428).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Zinc finger protein 428 (ZNF428).