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Zinc finger protein 430 (ZNF430)
- Target
- ZNF430
- Molecular classification
- Transcription factor, DNA-binding protein, Zinc finger protein (C2H2-type)
01
Overview
Zinc finger protein 430 is a DNA-binding transcription factor of the C2H2-type zinc finger protein family, predicted to regulate gene expression through sequence-specific binding to RNA polymerase II cis-regulatory regions and DNA, with a role in substantia nigra development and possible involvement in cancer[1][2][3][4]. It is a nuclear protein, part of the most prevalent class of zinc finger-containing transcription factors, which are central to gene regulatory networks and implicated in both normal development and tumorigenesis[1][2][3][4]. No evidence currently indicates it is directly druggable, nor are there known drugs or clinical biomarkers specifically targeting ZNF430[1].
- Other names
- ZNF430FLJ13659zinc finger protein 430
02
Biological functions
Transcriptional regulationDNA bindingRegulation of gene expressionInvolved in substantia nigra development
03
Disease associations
Cancer (diseases associated: breast leiomyosarcoma, breast liposarcoma)
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