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Target intelligence / Profile preview
Zinc finger protein 45 (ZNF45)
- Target
- ZNF45
- Molecular classification
- Transcription factor, DNA-binding protein, Zinc finger protein
01
Overview
Zinc finger protein 45 (ZNF45) is a member of the zinc finger protein family, which are defined by their characteristic zinc finger motifs that coordinate zinc ions and typically mediate DNA, RNA, or protein interactions[1]. ZNF45 is predicted to act as a DNA-binding transcription factor that regulates the expression of target genes by modulating DNA-templated transcription, and is predominantly located in the nucleoplasm[2][3]. Diseases associated with ZNF45 include retinal macular dystrophies. No evidence exists that ZNF45 functions as a therapeutic target, nor are its direct drug interactions, biomarker utility, or safety concerns currently documented[2][5].
- Other names
- Zinc finger protein 45ZNF45KOX5ZNF13BRC1744Zinc finger protein 13Zinc finger protein KOX5
02
Biological functions
Regulation of DNA-templated transcriptionDNA-binding transcription factor activityGene expression regulation
03
Disease associations
Macular dystrophy (Retinal, North Carolina type)Retinal macular dystrophy
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