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Zinc finger protein 454 (ZNF454)
- Target
- ZNF454
- Molecular classification
- Transcription factor, C2H2-type zinc finger protein
01
Overview
Zinc finger protein 454 is a human transcription factor that contains C2H2-type zinc finger motifs, enabling it to bind specific DNA sequences in a sequence-specific manner and regulate transcription by RNA polymerase II. Zinc finger proteins are a large and diverse family implicated in transcriptional regulation and various cellular processes, but ZNF454 itself has not been documented as a direct therapeutic target or biomarker. ZNF454 is encoded by the ZNF454 gene, also known as FLJ37444, and belongs to the C2H2-type class of zinc finger transcription factors. There is currently no documented role for ZNF454 in human diseases, drug interactions, or mechanisms of targeted therapy.
- Other names
- Zinc finger protein 454ZNF454FLJ37444
02
Biological functions
Sequence-specific DNA bindingRegulation of transcription by RNA polymerase IIPutative roles in gene regulation consistent with other zinc finger transcription factors
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