Target intelligence / Profile preview

Zinc finger protein 48 (ZNF48)

Target
ZNF48
Molecular classification
Transcription factor, Zinc finger protein, C2H2-type zinc finger protein
01

Overview

Zinc finger protein 48 (ZNF48) is a protein likely involved in transcriptional regulation, based on its structural classification as a C2H2-type zinc finger protein and by its inclusion in the largest transcription factor family in humans[5][2]. These proteins typically contain multiple zinc finger motifs that bind to specific regions of DNA and regulate gene expression[1][2][3]. ZNF48, like most family members, primarily functions by binding DNA to either promote or repress transcription, thereby contributing to the regulation of diverse cellular processes such as cell differentiation, proliferation, and patterning[2][4]. There is currently no evidence that ZNF48 is a direct therapeutic target, nor are there drugs or biomarkers specifically linked to this protein. The gene ZNF48 is one of many human zinc finger proteins, and while the family as a whole has been implicated in diseases like cancer and neurodegenerative disorders, there are no disease associations specific to ZNF48 reported in current literature[4][5].

Other names
Zinc finger protein 48ZNF48Zinc finger protein 553ZNF553DKFZp762K013FLJ31751MGC43952
02

Biological functions

Transcription regulationGene expression regulationDNA binding
03

Disease associations

Other (No direct role in major diseases reported; zinc finger proteins as a family are widely implicated in cancer, neurodegeneration, and other diseases, but ZNF48-specific evidence is lacking)

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