Zinc finger protein 483 (ZNF483)

Zinc finger protein 483 (ZNF483) is a member of the C2H2-type zinc-finger protein family and contains domains suggestive of a role in transcriptional regulation. It acts as a DNA-binding transcription factor, likely regulating the activity of RNA polymerase II at specific genomic loci. The gene is located on human chromosome 9 and is composed of various isoforms. While its precise biological roles and disease associations are not well-defined, it shares the typical structure and function of zinc finger transcription factors, which often participate in gene expression regulation. ZNF483 functions as a transcription factor and is not currently considered a typical therapeutic target such as a receptor, enzyme, transporter, or ion channel. There is no established link to approved drugs, biomarker utility, or known safety concerns in the literature reviewed.

Other names

ZNF483KIAA1962ZKSCAN16ZSCAN48HIT-10Zinc finger protein with KRAB and SCAN domains 16