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Zinc finger protein 486 pseudogene (ENSG00000271205) is a genomic sequence related to the zinc finger protein 486 gene in humans; however, it lacks the ability to encode a functional protein due to mutation or truncation. Zinc finger proteins typically possess DNA-binding domains and participate in transcriptional regulation, but pseudogenes like this one generally do not have these functional properties. Some pseudogenes can have regulatory roles in gene expression at the RNA level, but there is currently no evidence that this particular pseudogene has any biological function or relevance to drug targeting in humans[5][6]. The canonical zinc finger protein 486 gene (ZNF486) exists as a protein-coding gene (UniProt O75820), but “zinc finger protein 486 pseudogene” is not the active, functional form[6].
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