Target intelligence / Profile preview

Zinc finger protein 525 (ZNF525)

Target
ZNF525
Molecular classification
Transcription factor, Zinc finger protein
01

Overview

Zinc finger protein 525 (ZNF525) is a member of the large zinc finger protein family, characterized by the presence of zinc finger domains that enable DNA binding and transcriptional regulatory activity[1][2][4]. ZNF525 is predicted to function as a DNA-binding transcription factor, likely involved in modulating gene expression through sequence-specific interactions with DNA and potentially influencing transcription by RNA polymerase II[4]. Its canonical localization is nuclear. While the biological function of ZNF525 is not comprehensively mapped, expression signature studies identify it as part of a gene panel with prognostic significance in osteosarcoma, suggesting its expression pattern may contribute to cancer risk stratification rather than direct therapeutic targeting[3]. No direct drug interactions, therapeutic mechanisms of action, or specific safety issues are known for this target to date.

Other names
KIAA1979zinc finger protein 525ZNF525
02

Biological functions

Regulation of transcription by RNA polymerase IIDNA bindingPotential transcriptional regulation
03

Disease associations

Cancer (biomarker/prognostic role in osteosarcoma)Other (as general zinc finger family member impacting multiple cell processes)
04

Biomarkers

Prognostic biomarker in osteosarcoma (expression signature)

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