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Target intelligence / Profile preview
Zinc finger protein 527 (ZNF527)
- Target
- ZNF527
- Molecular classification
- Transcription factor, Zinc finger protein
01
Overview
Zinc finger protein 527 is a member of the zinc finger protein family, characterized by Cys2His2-type zinc finger domains that enable sequence-specific binding to DNA. ZNF527 functions as a transcription factor, potentially regulating gene expression by binding to cis-regulatory regions of genes transcribed by RNA polymerase II. This protein has many orthologues across species and several transcript variants, and may have diverse roles in cellular processes, but its precise biological functions and disease associations remain largely uncharacterized. There is no evidence supporting its status as a direct therapeutic target or involvement in drug interactions.
- Other names
- ZNF527KIAA1829Zinc finger protein 527zinc finger protein 527
02
Biological functions
DNA-binding transcription factor activityRNA polymerase II cis-regulatory region sequence-specific DNA bindingRegulation of gene expression
03
Disease associations
Other - No robust or widely acknowledged linkage to specific human diseases (such as cancer, inflammation, neurodegenerative disease, etc.) is documented at present; screens for essentiality in cancer cell lines exist, but do not establish clear disease relevance.
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