Target intelligence / Profile preview

Zinc finger protein 532 (ZNF532)

Target
ZNF532
Molecular classification
Transcription factor, C2H2-type zinc finger protein
01

Overview

Zinc finger protein 532 (ZNF532) is a nuclear protein predicted to function as a transcription factor, and is involved in the regulation of gene transcription by DNA binding[4][5][7]. It belongs to the large family of C2H2-type zinc finger proteins, which are characterized by their ability to bind DNA via zinc ion-stabilized finger-like motifs and thus regulate various transcriptional programs[3][5]. ZNF532 has been annotated as a regulator of DNA-templated transcription primarily through nucleic acid binding and is predominantly localized to the cell nucleus[4][5][7]. While many zinc finger proteins have established roles in genome stability and cancer, the specific biological and disease functions of ZNF532 remain incompletely characterized, though associations have been reported with certain cancers and inflammatory disorders[5][7]. No approved drugs directly target ZNF532, and there is no established biomarker or mechanism of action for potential therapeutics at this time.

Other names
KIAA1629FLJ10697ZNF532zinc finger protein 532
02

Biological functions

DNA bindingRegulation of transcription (DNA-templated)
03

Disease associations

Cancer (implicated as ZNF proteins broadly, some associations with specific subtypes such as Nut midline carcinoma and potentially others)Inflammatory bowel disease

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