Target intelligence / Profile preview

Zinc finger protein 546 (ZNF546)

Target
ZNF546
Molecular classification
Transcription factor, C2H2-type zinc finger protein
01

Overview

Zinc finger protein 546 (ZNF546) is a protein coding gene encoding a transcription factor characterized by C2H2-type zinc finger domains, facilitating sequence-specific DNA binding and regulation of gene expression, primarily as a modulator of RNA polymerase II-mediated transcription. ZNF546 is predicted to be active in the cell nucleus and may participate in key regulatory processes including transcriptional activation or repression, similar to other members of the zinc finger protein family. While some zinc finger proteins have roles in various cancers and other diseases, there is currently no direct evidence identifying ZNF546 itself as a therapeutic target, disease biomarker, or direct drug interactor.

Other names
Zinc finger protein 546ZNF546ZNF49MGC43537Zinc finger protein 49CTC-471F3.6
02

Biological functions

Transcription regulationGene expressionNucleic acid binding
03

Disease associations

Cancer (general references for zinc finger proteins)Glycogen storage disease IXb and IX (association with gene location, not necessarily causative)

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