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Target intelligence / Profile preview
Zinc finger protein 560 (ZNF560)
- Target
- ZNF560
- Molecular classification
- Transcription factor, Zinc finger protein (C2H2-type domain)
01
Overview
Zinc finger protein 560 (ZNF560) is a member of the zinc finger protein family characterized by the presence of C2H2-type zinc finger domains that enable DNA binding and transcriptional regulation. It is predicted to act as a sequence-specific transcription factor and localizes to the nucleus. ZNF560 is associated with transcriptional regulation via RNA polymerase II and is implicated in cancer biology, including osteosarcoma and prostate cancer, with higher expression linked to worse patient outcomes. It has no direct role as a receptor, enzyme, or transporter, and is not currently known to interact with specific drugs.
- Other names
- Zinc finger protein 560ZNF560FLJ31986ZN560_HUMANQ96MR9
02
Mechanism of action
Not applicable for drugs, but ZNF560 functions by binding DNA and regulating target gene transcription
03
Biological functions
Regulation of transcription by RNA polymerase IISequence-specific DNA bindingNuclear localization
04
Disease associations
Cancer (specifically associated with osteosarcoma prognosis and possibly prostate cancer)
05
Safety considerations
No specific safety concerns or therapeutic challenges noted since ZNF560 is not a direct drug target; however, its elevated expression is associated with poor outcomes in osteosarcoma, which may have prognostic relevance
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