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Zinc finger protein 583 (ZNF583)
- Target
- ZNF583
- Molecular classification
- Transcription factor (zinc finger family)
01
Overview
Zinc finger protein 583 (ZNF583) is a protein-coding gene in humans, predicted to encode a transcription factor featuring zinc finger domains. Zinc finger proteins constitute a large family with diverse functions, including DNA binding and modulation of gene transcription. ZNF583 is thought to participate in sequence-specific DNA binding and regulation of transcription by RNA polymerase II and is predicted to localize to the cell nucleus. There are no current reports of ZNF583 serving as a direct therapeutic target, disease biomarker, or drug target, though some gene-disease association data links ZNF583 to several carcinoma types.
- Other names
- ZNF583FLJ31030Zinc finger protein L3-5
02
Biological functions
Transcriptional regulation (likely involved in regulation by RNA polymerase II; specific roles are predicted rather than experimentally confirmed)
03
Disease associations
Preliminary association with some cancers (namely basosquamous carcinoma and anal squamous cell carcinoma)
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