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Zinc finger protein 585A (ZNF585A)
- Target
- ZNF585A
- Molecular classification
- Transcription factor, Krueppel C2H2-type zinc finger protein family
01
Overview
Zinc finger protein 585A (ZNF585A) is a member of the Krüppel C2H2-type zinc finger protein family, which is one of the largest superfamilies of DNA-binding proteins in eukaryotes[1][2]. ZNF585A acts as a predicted DNA-binding transcription activator with specificity for RNA polymerase II and is believed to be involved in the regulation of transcription[1]. It is primarily located in the nucleus[1]. ZNF585A has been associated with Ehlers-Danlos Syndrome, musculocontractural type, 1, but its roles in other diseases and biological processes are not well characterized[1]. There are currently no known drugs directly targeting ZNF585A, nor have specific biomarkers or safety concerns been described in the available literature. Alternative names include FLJ23765 and Zfp27[1][6].
- Other names
- ZNF585AFLJ23765Zfp27zinc finger protein 585A
02
Biological functions
Regulation of transcription by RNA polymerase IIDNA-binding transcription factor activityRNA polymerase II cis-regulatory region sequence-specific DNA binding
03
Disease associations
Ehlers-Danlos Syndrome, musculocontractural type, 1Other (roles in disease are largely uncharacterized)
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