Target intelligence / Profile preview

Zinc finger protein 592 (ZNF592)

Target
ZNF592
Molecular classification
Transcription factor, C2H2-type zinc finger protein
01

Overview

Zinc finger protein 592 is a human protein encoded by the ZNF592 gene. It is classified as a C2H2-type zinc finger protein, a major subgroup of transcription factors distinguished by multiple tandem zinc finger motifs that facilitate interactions with DNA, RNA, or other proteins[1][2]. ZNF592 is thought to be involved in regulating gene expression, particularly genes necessary for cerebellar development[1][5]. Mutations in this gene are linked to autosomal recessive spinocerebellar ataxia and have also been associated with other syndromes such as Galloway-Mowat syndrome 1 and Seckel syndrome[1][5]. While zinc finger proteins are broadly studied as genome stability regulators and potential therapeutic targets in cancer and DNA repair contexts, there is no current evidence indicating ZNF592 is a direct therapeutic target or that any drugs specifically interact with it[4][5].

Other names
ZNF592CAMOSSCAR5zinc finger protein 592
02

Biological functions

Regulation of gene expressionCerebellar developmentDNA bindingTranscriptional regulation
03

Disease associations

Neurodevelopmental disorder (autosomal recessive spinocerebellar ataxia)Galloway-Mowat syndrome 1Seckel syndrome

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