Zinc finger protein 597 (ZNF597)

Zinc finger protein 597 (ZNF597) is a protein with multiple zinc finger domains, primarily involved in transcriptional regulation by binding sequence-specific double-stranded DNA and zinc ions. The gene is imprinted and maternally expressed, with functions linked to neural development based on rodent studies. Defects or loss of related genes have been associated with disorders such as Mulchandani-Bhoj-Conlin Syndrome and chromosomal deletion syndromes. ZNF597 is a human protein coding gene with multiple zinc finger motifs, which are common in transcription factors and play roles in diverse processes including gene expression and DNA binding. The protein is thought to function mainly in the nucleus, regulating the transcription of target genes, although the precise biological pathways and regulated genes in humans remain incompletely characterized. There is currently no strong evidence that ZNF597 is a direct target for existing drugs or has established roles as a therapeutic target in disease. No direct interacting drugs, mechanisms of action for pharmacological intervention, biomarkers, or safety concerns have been described in available sources.

Other names

FLJ33071HIT-4