Target intelligence / Profile preview

Zinc finger protein 599 (ZNF599)

Target
ZNF599
Molecular classification
Transcription factor, Zinc finger protein
01

Overview

Zinc finger protein 599 is a member of the zinc finger protein family, characterized by the presence of zinc finger domains that facilitate DNA binding[3][6]. It is predicted to act as a DNA-binding transcription factor specific to RNA polymerase II, with a regulatory role in gene expression and transcriptional control[3][6]. The protein is localized in the nucleus and may participate in the modulation of other genes' transcriptional activity. ZNF599 is classified as a protein-coding gene and has been associated with clinical disorders such as chromosome 19q13.11 deletion syndrome and developmental and epileptic encephalopathy 52[3]. There is no current evidence indicating it is a primary therapeutic target or that any approved drugs directly interact with it[3][6].

Other names
ZNF599FLJ30663
02

Biological functions

Regulation of transcription by RNA polymerase IIDNA-binding transcription factor activityNucleic acid binding
03

Disease associations

Chromosome 19q13.11 deletion syndromeDevelopmental and epileptic encephalopathy 52

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