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Zinc finger protein 620 (ZNF620)
- Target
- ZNF620
- Molecular classification
- Transcription factor
01
Overview
Zinc finger protein 620 is a human protein encoded by the ZNF620 gene. It is predicted to function as a DNA-binding transcription factor, specifically regulating the activity of RNA polymerase II at sequence-specific transcription regulatory regions[1][2][5][6][7]. ZNF620 is believed to play a role in the regulation of gene expression within the nucleus, though its precise biological roles remain incompletely characterized[1][2][7]. Genetic associations have linked alterations in ZNF620 with myoclonic-atonic epilepsy and Pitt-Hopkins syndrome, suggesting possible involvement in neurodevelopmental processes[1]. No documented drugs are known to target ZNF620, and it is not currently considered a direct therapeutic target[1][6][7].
- Other names
- MGC50836zinc finger protein 620
02
Biological functions
Regulation of transcription by RNA polymerase IIDNA bindingRNA polymerase II-specific transcription factor activity
03
Disease associations
Myoclonic-atonic epilepsyPitt-Hopkins syndromeDevelopmental and epileptic encephalopathy
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