Zinc finger protein 621 (ZNF621)

Zinc finger protein 621 is a DNA-binding transcription factor encoded by the human ZNF621 gene on chromosome 3[4][2][7][8]. Like other zinc finger proteins, it is predicted to regulate transcription by binding DNA in a sequence-specific manner—specifically associated with RNA polymerase II cis-regulatory regions[2][5][7]. Zinc finger proteins as a class are structurally diverse and play key roles in gene expression, development, metabolism, and cellular differentiation, typically via their C2H2-type zinc finger motifs[1]. However, the specific biological roles, disease associations, and pharmacological relevance of ZNF621, as opposed to the broader family of zinc finger proteins, have not been well characterized, and to date, there are no known drugs or mechanisms of action targeting this gene[2][8]. There is no evidence that Zinc finger protein 621 is used as a therapeutic target or as a biomarker for disease or therapeutic efficacy[2].

Other names

Zinc finger protein 621ZNF621FLJ45246